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Index > Protein center > Map1b(Gene name) > Rat
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  • Map1b (Gene name),
  • Microtubule-associated protein 1B (Protein name ),  MAP1B_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Map1b;
    Protein name:
    Microtubule-associated protein 1B(MAP-1B);
    Alternative:
    Neuraxin;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. LC1 interacts with the amino-terminal region of MAP1B. Interacts with ANP32A and TIAM2. Interacts (via C-terminus) with GAN (via Kelch domains).
    Function:
    The function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    2459
    Sequence:
    50:
    MATVVVEATE | PEPSGSIGNP | AATTSPSLSH | RFLDSKFYLL | VVVGETVTEE | 
    100:
    HLRRAIGNIE | LGIRSWETNL | IECNLDQELK | LFVSRHSARF | SPEVPGQKIL | 
    150:
    HHRSDVLETV | VLINPSDEAV | STEVRLMITD | AARHKLLVLT | GQCFENTGEL | 
    200:
    ILQSGSFSFQ | NFIEIFTDQE | IGELLSTTHP | ANKASLTLFC | PEEGDWKNSN | 
    250:
    LDRHNLQDFI | NIKLNSASIL | PEMEGLSEFT | EYLSESVEVP | SPFDILEPPT | 
    300:
    SGGFLKLSKP | CCYIFPGGRG | DSALFAVNGF | NMLINGGSER | KSCFWKLIRH | 
    350:
    LDRVDSILLT | HIGDDNLPGI | NSMLQRKIAE | LEEESQGSTS | NSDWMKNLIS | 
    400:
    PDLGVVFLNV | PENLKNPEPN | IKMKRSTEEA | CFTLQYLNKL | SMKPEPLFRS | 
    450:
    VGNAIEPVIL | FQKMGVGKLK | MYVLNPVKSS | KEMQYFMQQW | TGTNKDKAEL | 
    500:
    ILPNGQEVDI | PISYLASVSS | LIVWHPANPA | EKIIRVLFPG | NSTQYNILEG | 
    550:
    LEKLKHLDFL | KQPLATQKDL | TGQVSTPPVK | QVKLKQRADS | RESLKPATKP | 
    600:
    LSSKSVRKES | KEEAPEATKA | SQVEKTPKVE | SKEKVIVKKD | KPGKVESKPS | 
    650:
    VTEKEVPSKE | EQSPVKAEVA | EKAATESKPK | VTKDKVVKKE | IKTKPEEKKE | 
    700:
    EKPKKEVAKK | EDKTPLKKDE | KPKKEEAKKE | IKKEIKKEEK | KELKKEVKKE | 
    750:
    TPLKDAKKEV | KKDEKKEVKK | EEKEPKKEIK | KISKDIKKST | PLSDTKKPAA | 
    800:
    LKPKVAKKEE | PTKKEPIAAG | KLKDKGKVKV | IKKEGKTTEA | AATAVGTAAV | 
    850:
    AAAAGVAASG | PAKELEAERS | LMSSPEDLTK | DFEELKAEEI | DVAKDIKPQL | 
    900:
    ELIEDEEKLK | ETEPGEAYVI | QKETEVSKGS | AESPDEGITT | TEGEGECEQT | 
    950:
    PEELEPVEKQ | GVDDIEKFED | EGAGFEESSE | AGDYEEKAET | EEAEEPEEDG | 
    1000:
    EDNVSGSASK | HSPTEDEEIA | KAEADVHIKE | KRESVASGDD | RAEEDMDEAL | 
    1050:
    EKGEAEQSEE | EGEEEEDKAE | DAREEDHEPD | KTEAEDYVMA | VVDKAAEAGV | 
    1100:
    TEDQYDFLGT | PAKQPGVQSP | SREPASSIHD | ETLPGGSESE | ATASDEENRE | 
    1150:
    DQPEEFTATS | GYTQSTIEIS | SEPTPMDEMS | TPRDVMTDET | NNEETESPSQ | 
    1200:
    EFVNITKYES | SLYSQEYSKP | VVASFNGLSD | GSKTDATDGR | DYNASASTIS | 
    1250:
    PPSSMEEDKF | SKSALRDAYR | PEETDVKTGA | ELDIKDVSDE | RLSPAKSPSL | 
    1300:
    SPSPPSPIEK | TPLGERSVNF | SLTPNEIKAS | AEGEATAVVS | PGVTQAVVEE | 
    1350:
    HCASPEEKTL | EVVSPSQSVT | GSAGHTPYYQ | SPTDEKSSHL | PTEVTENAQA | 
    1400:
    VPVSFEFTEA | KDENERSSIS | PMDEPVPDSE | SPIEKVLSPL | RSPPLIGSES | 
    1450:
    AYEDFLSADD | KALGRRSESP | FEGKNGKQGF | SDKESPVSDL | TSDLYQDKQE | 
    1500:
    EKRAGFIPIK | EDFSPEKKAS | DAEIMSSQSA | LALDERKLGG | DGSPTQVDVS | 
    1550:
    QFGSFKEDTK | MSISEGTVSD | KSATPVDEGA | EDTYSHMEGV | ASVSTASVAT | 
    1600:
    SSFPEPTTDD | VSPSLHAEVG | SPHSTEVDDS | LSVSVVQTPT | TFQETEMSPS | 
    1650:
    KEECPRPMSI | SPPDFSPKTA | KSRTPVQDHR | SEQSSMSIEF | GQESPEHSLA | 
    1700:
    MDFSRQSPDH | PTVGAGMLHI | TENGPTEVDY | SPSDIQDSSL | SHKIPPTEEP | 
    1750:
    SYTQDNDLSE | LISVSQVEAS | PSTSSAHTPS | QIASPLQEDT | LSDVVPPRDM | 
    1800:
    SLYASLASEK | VQSLEGEKLS | PKSDISPLTP | RESSPTYSPG | FSDSTSGAKE | 
    1850:
    STAAYQTSSS | PPIDAAAAEP | YGFRSSMLFD | TMQHHLALSR | DLTTSSVEKD | 
    1900:
    NGGKTPGDFN | YAYQKPESTT | ESPDEEDYDY | ESHEKTIQAH | DVGGYYYEKT | 
    1950:
    ERTIKSPCDS | GYSYETIEKT | TKTPEDGGYS | CEITEKTTRT | PEEGGYSYEI | 
    2000:
    SEKTTRTPEV | SGYTYEKTER | SRRLLDDISN | GYDDTEDGGH | TLGDCSYSYE | 
    2050:
    TTEKITSFPE | SESYSYETTT | KTTRSPDTSA | YCYETMEKIT | KTPQASTYSY | 
    2100:
    ETSDRCYTPE | RKSPSEARQD | VDLCLVSSCE | FKHPKTELSP | SFINPNPLEW | 
    2150:
    FAGEEPTEES | ERPLTQSGGA | PPPSGGKQQG | RQCDETPPTS | VSESAPSQTD | 
    2200:
    SDVPPETEEC | PSITADANLD | SEDESETIPT | DKTVTYKHMD | PPPAPMQDRS | 
    2250:
    PSPRHPDVSM | VDPEALAIEQ | NLGKALKKDL | KEKAKTKKPG | TKTKSSSPVK | 
    2300:
    KGDGKSKPSA | ASPKPGALKE | SSDKVSRVAS | PKKKESVEKA | MKTTTTPEVK | 
    2350:
    ATRGEEKDKE | TKNAANASAS | KSVKTATAGP | GTTKTAKSST | VPPGLPVYLD | 
    2400:
    LCYIPNHSNS | KNVDVEFFKR | VRSSYYVVSG | NDPAAEEPSR | AVLDALLEGK | 
    2450:
    AQWGSNMQVT | LIPTHDSEVM | REWYQETHEK | QQDLNIMVLA | SSSTVVMQDE | 
    2459:
    SFPACKIEL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat MAP-1B
    Cat.:
    E9938h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat MAP-1B
    Cat.:
    E9938m
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    Packing:
    96T
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    ELISA Kit for Rat MAP-1B
    Cat.:
    E9938r
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    Packing:
    96T
    Range:
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    CLIA Kit for Rat MAP-1B
    Cat.:
    U9938m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat MAP-1B
    Cat.:
    U9938h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat MAP-1B
    Cat.:
    U9938r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat MAP-1B
    Cat.:
    P9938Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MAP-1B
    Cat.:
    P9938Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MAP-1B
    Cat.:
    P9938Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat MAP-1B
    Monoclonal Antibody for Rat MAP-1B
    Monoclonal Antibody for Rat MAP-1B
    Protein for Rat MAP-1B
    Protein for Rat MAP-1B
    Protein for Rat MAP-1B

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    Linearity
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    References
    1. 1.
      "Isolation and sequencing of the 5' end of the rat microtubule-associated protein (MAP1B)-encoding cDNA."
      Liu D. , Fischer I.
      Gene171:307-308(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-142
      strain: Sprague-Dawley.
      tissue: Testis.
    2. 2.
      "Identification of two distinct microtubule binding domains on recombinant rat MAP 1B."
      Zauner W. , Kratz J. , Staunton J. , Feick P. , Wiche G.
      Eur. J. Cell Biol.57:66-74(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 96-2459;DOMAIN;INDUCTION
      strain: Sprague-Dawley.
      tissue: Brain.
      tissue: Glial tumor.
    3. 3.
      "Neuraxin, a novel putative structural protein of the rat central nervous system that is immunologically related to microtubule-associated protein 5."
      Rienitz A. , Grenningloh G. , Hermans-Borgmeyer I. , Kirsch J. , Littauer U.Z. , Prior P. , Gundelfinger E.D. , Schmitt B. , Betz H.
      EMBO J.8:2879-2888(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1541-2459;TISSUE SPECIFICITY
      tissue: Spinal cord.
    4. 4.
      "Differential regulation of microtubule-associated protein 1B (MAP1B) in rat CNS and PNS during development."
      Ma D. , Nothias F. , Boyne L.J. , Fischer I.
      J. Neurosci. Res.49:319-332(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;PHOSPHORYLATION
    5. 5.
      "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
      Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
      Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1906;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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