Protein name:
Microtubule-associated protein 1B (MAP-1B) ;
Alternative:
Neuraxin ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. LC1 interacts with the amino-terminal region of MAP1B. Interacts with ANP32A and TIAM2. Interacts (via C-terminus) with GAN (via Kelch domains).
Function:
The function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.
Subcellular Location:
Cytoplasm
cytoskeleton
Protein Attributes:
50:
MATVVVEATE | PEPSGSIGNP | AATTSPSLSH | RFLDSKFYLL | VVVGETVTEE |
100:
HLRRAIGNIE | LGIRSWETNL | IECNLDQELK | LFVSRHSARF | SPEVPGQKIL |
150:
HHRSDVLETV | VLINPSDEAV | STEVRLMITD | AARHKLLVLT | GQCFENTGEL |
200:
ILQSGSFSFQ | NFIEIFTDQE | IGELLSTTHP | ANKASLTLFC | PEEGDWKNSN |
250:
LDRHNLQDFI | NIKLNSASIL | PEMEGLSEFT | EYLSESVEVP | SPFDILEPPT |
300:
SGGFLKLSKP | CCYIFPGGRG | DSALFAVNGF | NMLINGGSER | KSCFWKLIRH |
350:
LDRVDSILLT | HIGDDNLPGI | NSMLQRKIAE | LEEESQGSTS | NSDWMKNLIS |
400:
PDLGVVFLNV | PENLKNPEPN | IKMKRSTEEA | CFTLQYLNKL | SMKPEPLFRS |
450:
VGNAIEPVIL | FQKMGVGKLK | MYVLNPVKSS | KEMQYFMQQW | TGTNKDKAEL |
500:
ILPNGQEVDI | PISYLASVSS | LIVWHPANPA | EKIIRVLFPG | NSTQYNILEG |
550:
LEKLKHLDFL | KQPLATQKDL | TGQVSTPPVK | QVKLKQRADS | RESLKPATKP |
600:
LSSKSVRKES | KEEAPEATKA | SQVEKTPKVE | SKEKVIVKKD | KPGKVESKPS |
650:
VTEKEVPSKE | EQSPVKAEVA | EKAATESKPK | VTKDKVVKKE | IKTKPEEKKE |
700:
EKPKKEVAKK | EDKTPLKKDE | KPKKEEAKKE | IKKEIKKEEK | KELKKEVKKE |
750:
TPLKDAKKEV | KKDEKKEVKK | EEKEPKKEIK | KISKDIKKST | PLSDTKKPAA |
800:
LKPKVAKKEE | PTKKEPIAAG | KLKDKGKVKV | IKKEGKTTEA | AATAVGTAAV |
850:
AAAAGVAASG | PAKELEAERS | LMSSPEDLTK | DFEELKAEEI | DVAKDIKPQL |
900:
ELIEDEEKLK | ETEPGEAYVI | QKETEVSKGS | AESPDEGITT | TEGEGECEQT |
950:
PEELEPVEKQ | GVDDIEKFED | EGAGFEESSE | AGDYEEKAET | EEAEEPEEDG |
1000:
EDNVSGSASK | HSPTEDEEIA | KAEADVHIKE | KRESVASGDD | RAEEDMDEAL |
1050:
EKGEAEQSEE | EGEEEEDKAE | DAREEDHEPD | KTEAEDYVMA | VVDKAAEAGV |
1100:
TEDQYDFLGT | PAKQPGVQSP | SREPASSIHD | ETLPGGSESE | ATASDEENRE |
1150:
DQPEEFTATS | GYTQSTIEIS | SEPTPMDEMS | TPRDVMTDET | NNEETESPSQ |
1200:
EFVNITKYES | SLYSQEYSKP | VVASFNGLSD | GSKTDATDGR | DYNASASTIS |
1250:
PPSSMEEDKF | SKSALRDAYR | PEETDVKTGA | ELDIKDVSDE | RLSPAKSPSL |
1300:
SPSPPSPIEK | TPLGERSVNF | SLTPNEIKAS | AEGEATAVVS | PGVTQAVVEE |
1350:
HCASPEEKTL | EVVSPSQSVT | GSAGHTPYYQ | SPTDEKSSHL | PTEVTENAQA |
1400:
VPVSFEFTEA | KDENERSSIS | PMDEPVPDSE | SPIEKVLSPL | RSPPLIGSES |
1450:
AYEDFLSADD | KALGRRSESP | FEGKNGKQGF | SDKESPVSDL | TSDLYQDKQE |
1500:
EKRAGFIPIK | EDFSPEKKAS | DAEIMSSQSA | LALDERKLGG | DGSPTQVDVS |
1550:
QFGSFKEDTK | MSISEGTVSD | KSATPVDEGA | EDTYSHMEGV | ASVSTASVAT |
1600:
SSFPEPTTDD | VSPSLHAEVG | SPHSTEVDDS | LSVSVVQTPT | TFQETEMSPS |
1650:
KEECPRPMSI | SPPDFSPKTA | KSRTPVQDHR | SEQSSMSIEF | GQESPEHSLA |
1700:
MDFSRQSPDH | PTVGAGMLHI | TENGPTEVDY | SPSDIQDSSL | SHKIPPTEEP |
1750:
SYTQDNDLSE | LISVSQVEAS | PSTSSAHTPS | QIASPLQEDT | LSDVVPPRDM |
1800:
SLYASLASEK | VQSLEGEKLS | PKSDISPLTP | RESSPTYSPG | FSDSTSGAKE |
1850:
STAAYQTSSS | PPIDAAAAEP | YGFRSSMLFD | TMQHHLALSR | DLTTSSVEKD |
1900:
NGGKTPGDFN | YAYQKPESTT | ESPDEEDYDY | ESHEKTIQAH | DVGGYYYEKT |
1950:
ERTIKSPCDS | GYSYETIEKT | TKTPEDGGYS | CEITEKTTRT | PEEGGYSYEI |
2000:
SEKTTRTPEV | SGYTYEKTER | SRRLLDDISN | GYDDTEDGGH | TLGDCSYSYE |
2050:
TTEKITSFPE | SESYSYETTT | KTTRSPDTSA | YCYETMEKIT | KTPQASTYSY |
2100:
ETSDRCYTPE | RKSPSEARQD | VDLCLVSSCE | FKHPKTELSP | SFINPNPLEW |
2150:
FAGEEPTEES | ERPLTQSGGA | PPPSGGKQQG | RQCDETPPTS | VSESAPSQTD |
2200:
SDVPPETEEC | PSITADANLD | SEDESETIPT | DKTVTYKHMD | PPPAPMQDRS |
2250:
PSPRHPDVSM | VDPEALAIEQ | NLGKALKKDL | KEKAKTKKPG | TKTKSSSPVK |
2300:
KGDGKSKPSA | ASPKPGALKE | SSDKVSRVAS | PKKKESVEKA | MKTTTTPEVK |
2350:
ATRGEEKDKE | TKNAANASAS | KSVKTATAGP | GTTKTAKSST | VPPGLPVYLD |
2400:
LCYIPNHSNS | KNVDVEFFKR | VRSSYYVVSG | NDPAAEEPSR | AVLDALLEGK |
2450:
AQWGSNMQVT | LIPTHDSEVM | REWYQETHEK | QQDLNIMVLA | SSSTVVMQDE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Polyclonal Antibody for Rat MAP-1B
Polyclonal Antibody for Rat MAP-1B
Polyclonal Antibody for Rat MAP-1B
Monoclonal Antibody for Rat MAP-1B
Monoclonal Antibody for Rat MAP-1B
Monoclonal Antibody for Rat MAP-1B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-142
strain :
Sprague-Dawley .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 96-2459;DOMAIN;INDUCTION
strain :
Sprague-Dawley .
tissue :
Brain .
tissue :
Glial tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1541-2459;TISSUE SPECIFICITY
tissue :
Spinal cord .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE;PHOSPHORYLATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1906;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]